Necrobiosis lipoidica as a cutaneous marker of underlying metabolic and autoimmune disorders: A case report

Vasileva, Mirela and Petrovska, Lidija and Spoa, Dimitar (2025) Necrobiosis lipoidica as a cutaneous marker of underlying metabolic and autoimmune disorders: A case report. International Journal of Science and Research Archive, 14 (3). pp. 253-255. ISSN 2582-8185

Introduction: Necrobiosis lipoidica is a very rare and chronic disease characterized by yellow-brown, atrophic, telangiectatic changes that occur mostly on the lower extremities. It is characterized by the appearance of collagen necrobiosis and dermal inflammation. Case report: A 50-year-old patient with changes on both lower legs that date back to a year ago and for which she never sought medical help complains of the appearance of an ulcer two weeks ago on one of the changes after a minor trauma. Conclusion: Necrobiosis lipoidica is a rare granulomatous disease associated with diabetes and autoimmune diseases that patients have already diagnosed, but in our case the skin changes were the first that led us to additional research and diagnosis of diabetes and rheumatoid arthritis.