Development of a Nutraceutical Tablet for prevention of thrombocytopenia

Gadhave, Pranjali D. and Tambe, Bhavana D. (2025) Development of a Nutraceutical Tablet for prevention of thrombocytopenia. International Journal of Science and Research Archive, 14 (2). pp. 1748-1753. ISSN 25828185

The growing prevalence of thrombocytopenia has created a critical need for safe, effective, and affordable treatment alternatives. Thrombocytopenia, characterized by a decreased platelet count, can result from various causes, including viral infections, autoimmune disorders, and bone marrow dysfunction. It increases the risk of severe bleeding, delayed wound healing, and immune system compromise. Medicinal plants have been widely used in traditional medicine systems for managing various health disorders. Among them, Carica Papaya (papaya) and Murrayakoenigii (curry leaves) have gained attention for their significant pharmacological properties. Papaya leaves contain bioactive compounds such as flavonoids, alkaloids, and papain enzymes, which have been reported to enhance platelet production, support immune function, and exhibit anti-inflammatory properties. Meanwhile, Murrayakoenigii is known for its anti-diabetic effects, primarily due to its rich content of carbazole alkaloids, flavonoids, and phenolic compounds, which help regulate blood glucose levels, improve insulin sensitivity, and reduce oxidative stress. This study focuses on formulating a nutraceutical tablet incorporating standardized extracts of Carica Papaya and Murrayakoenigii to offer a natural and effective approach to managing thrombocytopenia and diabetes. The formulation process includes the selection of optimal extraction methods, standardization of bioactive compounds, and evaluation of tablet stability, bioavailability, and therapeutic efficacy. The goal is to develop a plant-based nutraceutical that can serve as a complementary or alternative therapy, minimizing reliance on synthetic drugs.