A review of novel analytical methods for the determination of Vitamin B2 (Riboflavin)

This review highlights recent advancements in analytical techniques used for the determination of Vitamin B2 (riboflavin) in pharmaceuticals, foods, and biological samples. Various methods, including UV-Vis. spectrometry, fluorimetry, chromatography, mass spectrometry, and electrochemical techniques, are discussed. These methods leverage the unique properties of riboflavin, such as its fluorescence and redox potential, for accurate quantification. The review emphasizes the importance of these techniques in ensuring quality control and compliance with regulatory standards, while also exploring emerging trends like automation and green analytical chemistry.