Concomitant aspergillosis and pulmonary tuberculosis in an immunocompetent patient: A case study

Chakib, Lamia and Fikri, Oussama and Amro, Mohamed Ijim Lamyae (2025) Concomitant aspergillosis and pulmonary tuberculosis in an immunocompetent patient: A case study. World Journal of Advanced Research and Reviews, 25 (2). pp. 1337-1340. ISSN 2581-9615

Complex pulmonary infections pose a major clinical challenge, especially in patients with risk factors such as smoking, chronic lung diseases, or immunosuppression. Among these infections, tuberculosis (TB) and pulmonary aspergillosis are two commonly encountered respiratory conditions, but their association in the same clinical presentation remains relatively rare. The tuberculosis-aspergilloma co-infection, although less common, raises complex questions regarding therapeutic and diagnostic management. Clinical symptoms, such as cough, dyspnea, and chest pain, are common to many respiratory infections, making early diagnosis challenging without a thorough examination. Indeed, specialized diagnostic methods, such as chest computed tomography (CT) and bronchoscopy with analysis of bronchial aspirate, are often required to identify these multiple infections. The case presented in this article illustrates the importance of a comprehensive diagnostic approach to simultaneously identify two severe respiratory infections, tuberculosis and aspergilloma, in a 61-year-old patient. Prompt and appropriate management is essential to improve the patient's prognosis. Long-term follow-up is necessary to monitor pulmonary complications and the progression of the infection.