Literature review: Degradation characteristics of bioactive materials in oral environment

Dhaniswari, Salma Najmi and Artenia, Andi Amanda and Tedjosasongko, Udijanto and Rijanti, Devi (2025) Literature review: Degradation characteristics of bioactive materials in oral environment. World Journal of Advanced Research and Reviews, 25 (2). pp. 1012-1018. ISSN 2581-9615

Bioactive materials have been recognized as one of revolutionary advancements in the dental field due to its outstanding ability, such as enabling faster wound healing and tissue regeneration as well as enhancing dental remineralization. This literature review investigates bioactive materials' principles, behavior, and applications in dentistry focus on their interactions in the oral environment. The primary variables that affect the degradation include physicochemical, mechanical, and biological interactions, with salivary composition, pH variations, and biofilm emergence are all crucial. Current research gaps, including long-term clinical research and proficient in vivo testing simulations, are recognized, in addition to alternatives for future attempts to improve material properties and patient satisfaction. This review emphasizes the significance of knowing degradation processes of bioactive materials for long-term beneficial applications related to dentistry.