A review on clotrimazole in the treatment of fungal infection

Chandrakar, Bhumika and Sahu, Naveen Kumar and Prakash, Jyoti and Sahu, Rukhmani Raman and Rajput, Hariom and Sahu, Gyanesh Kumar (2025) A review on clotrimazole in the treatment of fungal infection. World Journal of Biology Pharmacy and Health Sciences, 23 (2). pp. 223-231. ISSN 2582-5542

Mycoses, another name for fungal infections, are caused by pathogenic fungi that can infect many regions of the human body. These infections can be classified as superficial, cutaneous, subcutaneous, or systemic; systemic infections can result in serious and potentially fatal diseases. Human infections are frequently caused by fungi, including dermatophytes, Aspergillus, Candida, and Cryptococcus. Immunocompromised conditions (e.g., HIV/AIDS, organ transplantation, chemotherapy), diabetes, and long-term use of corticosteroids or broad-spectrum antibiotics are risk factors for fungal infections. Depending on the species of fungus and the infection site, the clinical symptoms can range from minor skin diseases to serious, widespread infections that impact internal organs such as the heart, brain, and lungs. Molecular methods, microbiological cultures, and clinical examination are commonly used in diagnosis. Among the available treatments are antifungal.