Topical application fluoride for caries preventive

Bibi, Dewi Anggraeni and Primalia, Desy Rizkiani (2025) Topical application fluoride for caries preventive. World Journal of Advanced Research and Reviews, 27 (2). pp. 286-291. ISSN 2581-9615

Topical fluoride applications are a cornerstone of dental caries prevention, offering proven efficacy through multiple mechanisms. Fluoride enhances remineralization by forming acid-resistant fluorapatite, inhibits demineralization, and disrupts cariogenic bacterial activity. Common formulations include professional treatments like 5% sodium fluoride varnish (reducing caries by 30-45%) and daily-use fluoride toothpaste (1000-5000 ppm), which decrease caries incidence by 24-44%. While concerns about dental fluorosis exist, proper use minimizes risks, making fluoride safe for all ages. Emerging innovations like silver diamine fluoride (SDF) and nanoparticle-enhanced formulations show promise for improved delivery. Topical fluoride remains a cost-effective, versatile solution for caries prevention, supported by extensive evidence and global health guidelines.