Renal failure during pregnancy

Sbai, Rania and masrour, sarah and najwa, mikdam and Hamouche, Nabil and Chettati, Meriem and Fadili, Wafaa and Laouad, Inass (2025) Renal failure during pregnancy. GSC Advanced Research and Reviews, 22 (3). pp. 168-174. ISSN 2582-4597

Introduction: Acute renal failure in obstetric intensive care units is a diagnostic and therapeutic emergency. It is defined by the elevation during pregnancy of serum creatinine to ≥ 1 mg/dL or a rapid increase (in 48 h) of 0.5 mg/dL above the baseline value. The aim of our study is to describe the cases of renal failure, as well as to identify the factors associated with a poor prognosis. Patients and methods: This is a retrospective, descriptive and analytical study, covering a period of 3 years, from January 2021 to December 2023. It was carried out in the obstetric intensive care unit of the Mohammed VI University Hospital Center in Marrakech. Results: Ninety-nine patients were collected during the study period. The mean age of the patients was 30.55 ± 6.47 years (19 to 47 years). AKI in obstetric intensive care occurred more frequently in multigravida (73.8%) and multiparous (68.7%) patients. The etiologies of AKI in obstetric intensive care were, in order of frequency: pre-eclampsia (43.4%) and its complications, hemorrhagic shock (13.1%), acute hepatic steatosis during pregnancy (6.1%). The evolution was favorable with total recovery of renal function in 51.51%. While 37.3% of patients with partial recovery. Chronic kidney disease was observed in 3 patients. We also noted 2 maternal deaths. Conclusion: ARF in obstetric intensive care remains common in developing countries (4.2-15%). Pre-eclampsia, HELLP syndrome, eclampsia, hemorrhagic shock and sepsis represent its main etiologies