Verification of the Analytical Performance of the Serum Lipoprotein (a) Assay on the Abbott Alinity ci®: Experience of the Biochemistry Laboratory at Mohammed VI University Hospital of Oujda

Jamal, Kaoutar and kharkhach, Oumaima and Lekfif, Hasna and Moujtahide, Dounia El and Sebbar, El-Houcine and Choukri, Mohammed (2025) Verification of the Analytical Performance of the Serum Lipoprotein (a) Assay on the Abbott Alinity ci®: Experience of the Biochemistry Laboratory at Mohammed VI University Hospital of Oujda. GSC Biological and Pharmaceutical Sciences, 30 (3). 077-082. ISSN 2581-3250

The verification of analytical methods, as required by the ISO 15189 standard, allows for the evaluation and comparison of a method’s performance against predefined analytical objectives. This study focuses on verifying the assay of Lipoprotein (a) on the Abbott® Alinity analyzer, contributing to accreditation and quality improvement in the laboratory. The assay was performed using immunoturbidimetry. The evaluation of analytical performance (repeatability and intermediate precision) was conducted using two quality control levels, with results analyzed via BYG Informatique software. The obtained results show satisfactory repeatability with CV1 = 1.16% and CV2 = 0.44%. Intra-laboratory reproducibility is also satisfactory, with CV1 = 2.16% and CV2 = 1.29%, in line with the manufacturer's specifications.