Immunohistochemical analysis of Progesterone receptors in all Prostatic lesions, Case series study of 40 cases and review of Literature

Sodhi, Babita and Punj, Jyotsna (2025) Immunohistochemical analysis of Progesterone receptors in all Prostatic lesions, Case series study of 40 cases and review of Literature. World Journal of Advanced Research and Reviews, 27 (1). pp. 1609-1617. ISSN 2581-9615

Background: In scenario of scant data literature, this study was conducted for progesterone receptor as future hormone therapy in prostate lesions especially prostate cancer. Introduction: Prostate cancer as leading cause of mortality, progesterone receptor to be envisaged as future adjunct hormone therapy to reduce morbidity and mortality of prostate. Carcinoma prostate being heterogenous disease, not much is known about biological behaviour of Progesterone receptors. Material and methods: 40 cases of prostate, BHP, BHP with prostatitis, HGPIN and Adenocarcinoma were included where expressions of Progesterone receptors was carried out immunohistochemically. Conclusion: PR analysed as Good prognostic marker, can be authenticated as future adjunct hormone therapy, More Studies required to authenticate it, Our study has been adjunct to that