Green metric tools and white assessment in bioanalytical method development and validation: A comprehensive review

Gandu, Sravanthi and Gandla, Kumaraswamy and Repudi, Lalith (2025) Green metric tools and white assessment in bioanalytical method development and validation: A comprehensive review. World Journal of Advanced Research and Reviews, 26 (3). pp. 1674-1680. ISSN 2581-9615

Abstract

The increasing demand for sustainable and eco-friendly practices in pharmaceutical and bioanalytical research has prompted the integration of green chemistry principles into analytical method development. This review discusses the implementation of Green Analytical Chemistry (GAC) metrics, such as Analytical Eco-Scale, Green Analytical Procedure Index (GAPI), and Analytical Greenness (AGREE), as well as the emerging White Analytical Chemistry (WAC) concept, in the development and validation of bioanalytical methods. We highlight the significance, methodology, and applications of these tools in assessing the environmental impact, efficiency, and overall sustainability of bioanalytical procedures. Case studies from recent literature are examined to illustrate practical applications and future directions.

Item Type: Article
Official URL: https://doi.org/10.30574/wjarr.2025.26.3.2362
Uncontrolled Keywords: Green Analytical Chemistry; White Analytical Chemistry; Bioanalytical Methods; Method
Date Deposited: 01 Sep 2025 12:05
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URI: https://eprint.scholarsrepository.com/id/eprint/4255