Mefenamic acid and renal health: Unveiling the risks

Wilson, Sharon and Kodiattu, Sara Kurien and Harikrishnan, S and Rojin, Kavya Annie and Jesurun, R S Jacob (2025) Mefenamic acid and renal health: Unveiling the risks. World Journal of Biology Pharmacy and Health Sciences, 23 (1). pp. 323-328. ISSN 2582-5542

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Abstract

Mefenamic acid is a non-selective non-steroidal anti-inflammatory drug (NSAIDs) used in the management of pain and inflammation. They are non-opioid analgesics. They inhibit the synthesis of prostaglandins in body tissues by inhibiting COX-1 and COX-2. Thus inhibits the synthesis of prostaglandins, reducing blood supply to the kidneys. Hence, there is always a possibility of kidney injury after administration of Mefenamic acid. We hereby present a series of 7 patients where they developed kidney injury while on treatment with Mefenamic acid.

Item Type: Article
Official URL: https://doi.org/10.30574/wjbphs.2025.23.1.0679
Uncontrolled Keywords: Mefenamic Acid; NSAID; Pain and Inflammation; CKD; Acute Kidney Injury; DIKI
Depositing User: Editor WJBPHS
Date Deposited: 20 Aug 2025 12:16
Related URLs:
URI: https://eprint.scholarsrepository.com/id/eprint/4154