Mebeverine hydrochloride in pharmaceutical preparation as determined by spectrophotometer using the Ion Association Reaction

Hussein, Nahlah Jaber and Al-Bahrani, Hussein Ali and Sabi, Ali A. (2025) Mebeverine hydrochloride in pharmaceutical preparation as determined by spectrophotometer using the Ion Association Reaction. International Journal of Science and Research Archive, 14 (1). pp. 146-152. ISSN 25828185

[thumbnail of IJSRA-2025-0066.pdf] Text
IJSRA-2025-0066.pdf - Published Version
Available under License Creative Commons Attribution Non-commercial Share Alike.

Download (670kB)

Abstract

A simple, accurate, and sensitive colorimetric method for determining Mebeverine HCL. Pure and pharmaceutical preparations have been developed. The method is based on the formation of an ion-association combination between picric acid and the medication. The range was measured with the maximum absorption at 382.00 nm. With a molar absorptivity of 3.41×104 Mol L-1cm-1, a relative standard deviation (RSD %) of 0.6430 percent, a mean recovery of 90.776-98.055%, and a correlation value of Between 1.0 and 30.0 µg/ml, the beer's law is observed (r2 = 0.990). This method successfully identified mebeverine HCL in pharmaceutical formulations and bulk.

Item Type: Article
Uncontrolled Keywords: Spectrophotometric Determination; Mebeverine HCL; Picric Acid
Subjects: Q Science > Q Science (General)
R Medicine > RS Pharmacy and materia medica
Depositing User: Editor IJSRA
Date Deposited: 05 Jul 2025 15:07
Last Modified: 05 Jul 2025 15:07
URI: https://eprint.scholarsrepository.com/id/eprint/41

Actions (login required)

View Item
View Item