An unusual discovery: Aberrant subclavian artery - symptoms, embryological pathology, surgical approach, and outcome analysis

Saheen KV, Muhammed and Kumar, Yasvanth and Swaminathan, V and Solomon, Neville AG (2025) An unusual discovery: Aberrant subclavian artery - symptoms, embryological pathology, surgical approach, and outcome analysis. World Journal of Biology Pharmacy and Health Sciences, 22 (3). pp. 386-390. ISSN 2582-5542

Introduction: Aberrant subclavian artery (ASA) anomalies, though rare, present unique challenges in clinical practice due to their varied clinical manifestations and associated anatomical complexities. This study aims to comprehensively elucidate the embryological basis, clinical spectrum, diagnostic modalities, management strategies, and outcomes of ASA anomalies. Methods: A retrospective analysis was conducted on pediatric patients diagnosed with ASA anomalies between 2019 and 2023. Clinical data, including presenting symptoms, diagnostic findings, management approaches, and post-operative outcomes, were collected and analyzed. Results: Four pediatric patients with ASA anomalies were included in the study, with three cases of aberrant right subclavian artery and one case of aberrant left subclavian artery. Most patients were presented with dysphagia secondary to esophageal compression, while associated anomalies such as Kommer ell’s diverticulum and cardiac anomalies were commonly observed. Diagnostic modalities including prenatal ultrasound, CT angiography, and barium swallow studies aided in accurate diagnosis and evaluation of associated anatomical variations. Management strategies ranged from conservative measures to surgical interventions, with the hybrid approach demonstrating promising outcomes. Post-operative recovery was generally uneventful, with isolated cases of complications resolving spontaneously.