Genetic and epigenetic factors contributing to the development of PCOD

Inamdar, Saba Shahjahan and Kate, Prajkta Annasaheb and Shinde, Sanket Pandurang (2025) Genetic and epigenetic factors contributing to the development of PCOD. World Journal of Biology Pharmacy and Health Sciences, 22 (3). 016-020. ISSN 2582-5542

Globally five to ten percent of women who are of reproductive age suffer from Polycystic Ovary Disease, a complicated endocrine disease marked by irregular menstrual periods, hyperandrogenism, and polycystic ovarian morphology. We explore the significance of insulin resistance, metabolic syndrome, and psychosocial comorbidities in addition to talking about the genetic, hormonal, and environmental variables that contribute to PCOD. The most recent diagnostic standards, such as the Rotterdam criteria, are examined, and various forms of treatment including lifestyle changes, medications, and surgery are assessed critical. Emphasis is placed on recent developments in our knowledge of the molecular mechanism behind PCOD and new treatment targets