Pharmacological evaluation of the anti-ulcer and anti-arthritic potential of ethanolic extract of acalypha indica linn

SENTHILKUMAR, S. and SINGH, P. KUMAR and RANI, C. KIRUBA (2025) Pharmacological evaluation of the anti-ulcer and anti-arthritic potential of ethanolic extract of acalypha indica linn. World Journal of Biology Pharmacy and Health Sciences, 22 (2). pp. 147-154. ISSN 2582-5542

The objective of present study to evaluate the anti-ulcer and anti-arthritic activity of ethanolic leaf extract of Acalypha indica. The anti-ulcer activity of ethanolic extract of Acalypha indica was investigated by pylorous ligation and indomethacin induced gastric ulcer in rats. The cause of ulceration in patients is mainly due to hyper secretion of gastric acid and pepsin. Acalypha indica plant extract some of the most attractive sources of new drugs and have been shown to produce promising results in the treatment of gastric ulcers. Rheumatoid arthritis is a systemic auto immune disease characterized by articular inflammation that eventually leads to the destructions of joints. The present work is aimed to evaluate the anti-arthritic effect of plant Acalypha indica extract by Freund’s Complete Adjuvant (FCA) induced arthritis in rats. Medicinal plants possess numerous active phyto constituents that are responsible for several biological activities. Acalypha indica is very important medicinal plant, to possess anti-ulcer and anti-arthritic activity.