A solitary brain metastasis from papillary carcinoma of thyroid: Case report

Unais, CT and Raiyani, Yatin V and Balamurugan, M (2025) A solitary brain metastasis from papillary carcinoma of thyroid: Case report. World Journal of Biology Pharmacy and Health Sciences, 22 (1). pp. 350-355. ISSN 2582-5542

Background: Brain metastasis from papillary thyroid carcinoma is very rare and has a bad prognosis. There is no standard diagnostic treatment protocol for brain metastatic papillary thyroid carcinoma. Here we present a case report of Solitary brain metastasis from papillary carcinoma. Case report:A 52-year-old woman who had undergone a near total thyroidectomy with left functional neck dissection and high-dose radioiodine therapy for papillary thyroid carcinoma with regular follow-up. She presented with headaches with raised intracranial pressure symptoms. Magnetic Resonance Imaging (MRI) of brain revealed left temporal space occupying lesion. I131 scan was negative. She underwent a craniotomy and a gross total excision of the lesion. Histopathological diagnosis confirmed as papillary thyroid carcinoma. Conclusion: This is a rare case of brain metastasis from papillary thyroid cancer. MRI is the best imaging tools for screening and diagnosis when compared to other techniques. Surgery and stereotactic radiosurgery are the main treatments.