Drug utilisation and evaluation of medicine

Thennavan, T and Uma, R and ManoRanjani, A and Eugin, J and Viruthakrishwar, B and Yogeshwaran, B and Cherian, Angel and Nithya, K (2025) Drug utilisation and evaluation of medicine. World Journal of Biology Pharmacy and Health Sciences, 21 (3). pp. 442-451. ISSN 2582-5542

Background: Inappropriate medication use can lead to adverse drug events, reduced therapeutic outcomes, and increased healthcare costs. Drug Utilization Review (DUR) is a systematic process aimed at optimizing medication use. Objective: To evaluate the impact of DUR on medication use patterns and patient outcomes in a tertiary care setting. Methods: A retrospective, observational study was conducted, analyzing 100 prescriptions over a 3-month period. Clinical pharmacists performed DUR, identifying potential medication-related problems and recommending interventions. Results: DUR indicates that drug interactions are a significance concurrent in the patient's current treatment regimen, with 63 prescription drug interacted and 37 not interacted, thus it leading to improved patient outcomes and reduced healthcare costs. Conclusion: This study demonstrates the effectiveness of DUR in optimizing medication use, enhancing patient safety, and promoting cost-effective prescribing practices.