Recent updates on antimicrobial, antifungal, and anti-cancerous agents from natural herbs of Indian Himalaya

Singha, Arun and Minhas, Bharti and Minhas, Naveen and Kumar, Nitesh (2025) Recent updates on antimicrobial, antifungal, and anti-cancerous agents from natural herbs of Indian Himalaya. World Journal of Biology Pharmacy and Health Sciences, 21 (3). pp. 397-411. ISSN 2582-5542

Indian Himalayas harbor a rich biodiversity of natural herbs that have been integral to traditional healing practices, cultural customs, and ecological balance for millennia. This chapter emphasizes the antimicrobial, antifungal, and anticancerous properties of herbs native to the Indian Himalayas, highlighting their significance in healthcare, scientific research, and cultural heritage. Traditional knowledge systems such as Ayurveda have long recognized the therapeutic benefits of herbs like Tulsi, Brahmi, and Ashwagandha, which play crucial roles in treating various ailments and enhancing overall well-being. Moreover, the cultivation and trade of Himalayan herbs contribute significantly to local economies while promoting sustainable harvesting practices guided by indigenous wisdom. Herbs offer promising alternatives or complements to conventional antimicrobial agents, addressing challenges such as antimicrobial resistance. Garlic, tea tree oil, neem, and oregano are among the herbs renowned for their antimicrobial and antifungal properties, supported by scientific research. Additionally, herbs like turmeric and green tea exhibit potent anticancerous properties, providing avenues for novel cancer treatments. The exploration of antimicrobial agents, including antibiotics, antivirals, antifungals, and antiparasitics underscores the ongoing quest to combat infectious diseases and emerging antimicrobial resistance. Herbs offer a diverse array of bioactive compounds that target microorganisms through multiple mechanisms of action, minimizing the risk of resistance development. Synergistic herbal combinations further enhance antimicrobial efficacy, reflecting the holistic approach of traditional medicine systems. The study of natural herbs for medicinal purposes transcends disciplinary boundaries, encompassing botany, pharmacology, chemistry, ethnobotany and traditional medicine systems. Interdisciplinary collaboration is essential for unlocking the full potential of medicinal plants, promoting evidence-based healthcare practices, and fostering sustainability. By embracing traditional wisdom and scientific innovation, we can harness the healing gifts of nature to promote health, preserve biodiversity and nurture the connection between humanity and the natural world.