Guillain barre syndrome: A comprehensive review and a case report

Hemalatha, Ganjala and Anusha, Nakka and Sathwika, Manchikanti Hima and Aafreen, Shaik Uzma and Gayatri, Nakka and Mohana, Kollipara (2025) Guillain barre syndrome: A comprehensive review and a case report. World Journal of Biology Pharmacy and Health Sciences, 21 (3). pp. 226-233. ISSN 2582-5542

A 58-year-old male patient who had been complaining of weakness in his upper and lower limbs for three days was taken to the hospital. On examination, he had decreased muscle strength in both upper and lower limbs (4/5). MRI brain [plain] reveals acute CVA, left hemiparesis, small vessel changes in bilateral centrum semiovale, chronic lacunar infarct, left lentiform nucleus, and left corona radiata. The patient's complete blood count [CBC] revealed abnormal RBC, haemoglobin, PCV, MCH, and RDW levels. The patient has abnormal CRP and serum potassium levels. And the patient was diagnosed with Gullain barre syndrome. He received intravenous immunoglobulin [IVIG], plasma exchange, nutritional supplements, NSAIDs, anticonvulsants, and corticosteroid treatment. . Your immune system may unintentionally attack a component of your peripheral nervous system—the system of neurons that are not an element of your cerebral cortex or vertebral cord— It may result in Guillain-Barre syndrome (GBS), an uncommon neurological condition. Guillain-Barre syndrome is an illness that can be lethal. The patients require close monitoring and the quickest possible treatment. GBS consequences can result in mortality in just a few percent of individuals, even under the best of circumstances.