Formulation and evaluation of antimicrobial herbal gel

Purkar, Poonam Yogesh and Ingale, Pramod and Batwal, Kajal and Rathod, Sainath and Gaikwad, Yash (2025) Formulation and evaluation of antimicrobial herbal gel. World Journal of Biology Pharmacy and Health Sciences, 21 (2). pp. 288-294. ISSN 2582-5542

The aim of the current study to formulate and evaluate topical herbal gel of betel leaves and giloy. There is a potential market demand for natural and plant-based skin care products. The antimicrobial gel made from herbal plants works better than synthetic medications and has fewer side effects. The prepared extracts of betel piper leaves and giloy were added to prepared simple carbopol gel. The microorganismsS. aureus, B. subtilis, E. coli and P. aeruginosa have been used to determine antimicrobial activity. Candida albicans has been used to test its antifungal activity. This formulated gel was evaluated for physicochemical properties, pH determination, spreadability, viscosity, antimicrobial and antifungal activities. The results demonstrate that herbal gel containing betel leaves and giloy extract was successfully formulated. The gel was very effective as an antimicrobial and antifungal formulation. These formulations which are easy to use and have no side effects, have the potential to be very promising medications for wound healing.