Clinical validation of safety and effectiveness of De-Stress and Perform Tablet

Mulik, Sachin Baburao and Soni, Kriti and Ganu, Gayatri Pramod (2025) Clinical validation of safety and effectiveness of De-Stress and Perform Tablet. World Journal of Biology Pharmacy and Health Sciences, 21 (2). 008-016. ISSN 2582-5542

Introduction: Numerous physical and mental health issues have been linked to stress, making it a major global health concern. Natural alternatives have the ability to lessen stress and enhance brain function. This study aims to establish clinical proof of De-Stress & Perform Tablet’s efficacy and safety. Materials and Methods: An open-label, non-randomized study was conducted on thirty healthy male subjects. Each subject received one bottle containing 30 De-Stress & Perform tablets for 30 days. The research objectives were to evaluate changes in CBC (Complete Blood Count), LFT (Liver Function Test), and RFT (Renal Function Test) parameters, sexual desire using the Sexual Desire Inventory (SDI) score, Perceived Stress Scale (PSS) score, and self-reported stamina on a 4-point Likert scale were evaluated at screening and day 30. Results: After 30 days of treatment, white blood cell (WBC) count, creatinine, and uric acid levels decreased, while Mean Corpuscular Hemoglobin Concentration (MCHC) and urea levels increased; these changes were statistically significant but clinically insignificant. Other hematological and liver function parameters remained within normal ranges, with no statistically or clinically significant changes. Vital signs were stable, perceived stress decreased by 61.35% (p < 0.001), self-reported stamina improved, and sexual desire increased by 62.34% (p < 0.001). All participants demonstrated excellent tolerability, and no adverse events were attributed to the investigational product. Conclusion: The De-Stress & Perform Tablet was well-tolerated and safe in healthy males, with no clinically significant adverse effects. It also demonstrated efficacy in reducing stress, enhancing stamina, and increasing sexual desire.