A review of phyto therapeutic approaches to manage skin complications in immune deficiency

Chandra, Yadala Prapurna and Kavyasudha, Kongi and Reenu, Shaik Fathima (2025) A review of phyto therapeutic approaches to manage skin complications in immune deficiency. World Journal of Biology Pharmacy and Health Sciences, 21 (1). pp. 541-546. ISSN 2582-5542

Human skin, the largest organ of the body, plays a crucial role in immune defense and homeostasis. This review explores the phyto-therapeutic approaches for managing skin entanglements related with immune deficiency, including conditions such as psoriasis, eczema, and vitiligo. The skin functions as an immune organ, housing various immune cells that engage in surveillance and response to pathogens. However, a compromised immune system can lead to increased susceptibility to skin disorders. Allopathic medicines, while effective, often come with significant side effects and risks, prompting a growing interest in herbal medicine as a safer alternative. This review analyzes the logical proof supporting the utilization of different natural phytomedicines, their mechanisms of action, and their potential benefits in treating skin diseases. A comprehensive table highlights key herbal plants, their dynamic constituents and their applications in skin issues accentuating their calming and immunomodulatory properties. The findings suggest that herbal remedies, such as neem, turmeric, and aloe vera, offer promising therapeutic options with minimal side effects. However, further research is needed to validate their efficacy and safety in clinical settings. This review aims to provide insights into the advantages and limitations of phytotherapy, paving the way for future research directions and therapeutic strategies in dermatology.