Retrospective cohort study- a gender-based analysis of symptom severity and age correlation in nasal septum deviation

Nadaf, Afiya Afrin and Pranavi, Chepyala and Abhinaya, Dhadi and Dholi, Shravan Kumar (2025) Retrospective cohort study- a gender-based analysis of symptom severity and age correlation in nasal septum deviation. World Journal of Biology Pharmacy and Health Sciences, 21 (1). pp. 422-426. ISSN 2582-5542

A deviated septum (NSD) can lead to nasal obstruction and is often associated with genetic connective tissue disorders. This study investigates the occurrence and severity of nasal symptoms across genders, examining potential influences of sexuality. Methodology: Conducted at Chalmeda Anandh Rao Institute of Medical Sciences, Karimnagar, over six months, this study involved participants meeting specific inclusion criteria. The Nasal Obstruction Symptom Evaluation (NOSE) Scale was utilized to assess symptoms in individuals with NSD. Results: A total of 264 participants were analyzed, with females comprising 59.84% and males 38.63%. The highest prevalence of NSD was observed in the 21-30 age group, while the lowest occurred in those aged 10 years (0.71%). Women exhibited more severe symptoms than men, with nasal congestion/stuffiness (98.71%) and sleep disturbances (98.7%) being the most common complaints. Conclusion: NSD is a prevalent condition, particularly affecting women aged 21 to 40 more than their male counterparts and other age groups. This suggests the possibility of gender-specific factors or hormonal influences contributing to the development of NSD in this demographic. The findings underscore the importance of gender considerations in understanding and managing nasal abnormalities.