The Sinclair method: The need for integrated and holistic approaches in alcohol treatment and recovery

Merron, S.J.L. and Garrason, Carol and Duyvenvoorde, Joanna and Duyvenvoorde, Adrian Mark and Hart, Susannah and Javaid, Amin (2025) The Sinclair method: The need for integrated and holistic approaches in alcohol treatment and recovery. World Journal of Biology Pharmacy and Health Sciences, 21 (1). pp. 268-273. ISSN 2582-5542

The world’s consumption of alcohol per capita in 2016 among male and female drinkers worldwide was on average 19.4 litres of pure alcohol for males and 7.0 litres for females, and three million deaths worldwide are attributable to alcohol each year. The pathology of alcoholism and addiction has been a source of medical and psychological interest for nearly two centuries. This article provides a summary of genetic and neurobiological research, along with a comparison of a variety of treatment methods employed including the 12-step abstinence program, holistic approaches, and modern advances of pharmacotherapy interventions, such as the Sinclair Method.