Primary non-Hodgkin lymphoma of the palatine tonsil: Case report and review of the literature

Ezadine, Mouhamad and Moctar, Wah Sidi El and Bencheikh, Razika and Benbouzid, Mohammed Anas and Essakalli, Leila (2025) Primary non-Hodgkin lymphoma of the palatine tonsil: Case report and review of the literature. World Journal of Advanced Research and Reviews, 25 (1). pp. 1373-1377. ISSN 2581-9615

Primary non-Hodgkin lymphoma of the palatine tonsil is a rare but important form of extranodal lymphoma, with diffuse large B-cell lymphoma (DLBCL) being the most common subtype. We present a case of a 44-year-old male diagnosed with localized DLBCL of the left tonsil, confirmed through biopsy and treated with chemotherapy. Early diagnosis is challenging due to nonspecific symptoms such as tonsillar enlargement and cervical lymphadenopathy. Treatment typically involves chemotherapy, with radiotherapy used for localized or low-grade cases. Aggressive disease may require higher radiation doses. Early detection and personalized treatment plans are key to achieving favorable outcomes.