The evolution and impact of manufacturing execution systems in pharmaceutical manufacturing

Dhage, Sarita Santosh (2025) The evolution and impact of manufacturing execution systems in pharmaceutical manufacturing. World Journal of Advanced Research and Reviews, 26 (1). pp. 3494-3500. ISSN 2581-9615

This article examines the evolution and impact of Manufacturing Execution Systems (MES) in the pharmaceutical manufacturing sector. It investigates how these comprehensive software solutions bridge the gap between enterprise planning systems and production floors, providing real-time monitoring capabilities and enhancing regulatory compliance. The article explores the core functions and key components of pharmaceutical MES platforms, identifies the primary factors driving adoption, discusses implementation challenges, and presents an outlook on emerging trends that are beginning to reshape the landscape. By addressing regulatory compliance, operational efficiency, and product quality concerns, MES has transformed from a simple tracking tool to an essential component of digital transformation in pharmaceutical operations, with a practical perspective on how manufacturers with traditional systems can prepare for future technological advancements through incremental approaches.