A study to assess the knowledge and expected outcome on guidelines directed to medical therapy in heart failure patient undergoing treatment in IP and OP basis at Apollo DRDO hospitals, Hyderabad

Leena, C L and Reddy, R Sreekanth and Nirmala, G. and Nishitha, O. and Flinsi, D. Maryline (2025) A study to assess the knowledge and expected outcome on guidelines directed to medical therapy in heart failure patient undergoing treatment in IP and OP basis at Apollo DRDO hospitals, Hyderabad. International Journal of Science and Research Archive, 15 (2). pp. 472-479. ISSN 2582-8185

Heart failure is a complex clinical condition. Optimal use of guideline-directed medical therapy (GDMT) can prevent hospitalization and mortality among patients with heart failure (HF). Although the guidelines-directed medical therapy for heart failure patients may incur slightly higher expenses, our primary concern was ensuring patients' adherence to this therapy. By conducting this research, we aimed to determine whether adherence to these guidelines would lead to improved patient outcomes and decreased mortality. The study conducted at Apollo DRDO Hospital in Hyderabad selected 60 patients using the purposive sampling technique. Data was collected with the help of informed knowledge questionnaires with the permission from Nursing Head and Ethical approval from Apollo Hospital Jubilee hills. Patients undergoing treatment for heart failure were administered a knowledge & attitude questionnaire before and after receiving guideline-directed education. Paired t-test analysis revealed a significant improvement in knowledge attitude scores. The result showed that the mean difference in knowledge scores pre- and post-intervention was 1.93, with a paired t-test value of 10.72 (p < 0.05). This improvement exceeded the critical t-value of ±2.001, indicating a statistically significant enhancement in knowledge. The mean difference in attitude scores pre- and post-intervention was 1.48, with a paired t-test value of 7.75 (p < 0.05), indicating significant improvement in attitude score. And among 60 patients, 6 patients (10%) were readmitted to the hospital and 1 patient (1.67%) died. These findings demonstrate that Guideline-Directed to Medical Therapy (GDMT) is effective in improving outcomes in patients with heart failure and a substantial improvement in quality of life.