Association between menopause and quality of life: A cross-sectional study using data from women living in Northern Greece

Sousamli, Aikaterini E and Dourou, Panagiota D (2025) Association between menopause and quality of life: A cross-sectional study using data from women living in Northern Greece. World Journal of Advanced Research and Reviews, 25 (3). pp. 1377-1388. ISSN 2581-9615

Menopause represents a significant life transition for women. Given the prolongation in women’s life expectancy, they will spend a large period of their lives in the postmenopausal stage. The lack of female hormones causes physical and psychological symptoms that negatively affect quality of life. Common vasomotor symptoms include hot flashes, night sweats, sleep disturbances, sexual dysfunction, and weight gain, while psychological symptoms involve anxiety, depression, and irritability. This study aimed to evaluate menopausal symptoms and their effect on women’s quality of life. The study sample consisted of 100 menopausal and 101 non-menopausal women aged 45-55. An anonymous questionnaire included sociodemographic questions, the DASS-21 index, MENQOL index, Pittsburgh Sleep Quality Index, SF-12 questionnaire, HFRS index and FSFI index. Results showed menopausal women had higher anxiety, stress, and depression levels (P<0.001) and poorer sleep quality (48.4% vs. 18%, P<0.001) compared to non-menopausal women. Non-menopausal women had better physical and mental health (P<0.001) and higher sexual desire. Increased physical and sexual menopausal symptoms correlated with poorer physical health (P<0.001), while psychosocial symptoms were linked to worse mental health (P<0.001). Menopause is associated with anxiety, stress, depression, poor sleep, and sexual dysfunction, reducing quality of life. Healthcare providers must guide women and suggest treatments based on their health history and preferences. Lifestyle changes, including a healthy diet and exercise, can help alleviate symptoms and improve well-being.