Case series: High-risk pregnancy monitoring in cases of pregnant women with reactive Hepatitis B

Dewi, Setyowati and Desy, Arysandy Monicha and Dyah, Wittiarika Ivon (2025) Case series: High-risk pregnancy monitoring in cases of pregnant women with reactive Hepatitis B. World Journal of Advanced Research and Reviews, 25 (3). pp. 702-707. ISSN 2581-9615

Objectives: Chronic Hepatitis B remains a global health issue, with 254 million individuals affected and 1.1 million deaths annually. In East Java, the prevalence of Hepatitis B among pregnant women reached 5.2% in 2023, indicating a significant risk of vertical transmission. Managing Hepatitis B during pregnancy requires a comprehensive approach to prevent complications and transmission to the newborn. Case Series: This case report involves a 35-year-old woman, 30 weeks pregnant in her fifth pregnancy diagnosed with reactive Hepatitis B and a complex obstetric history, including multiple abortions and retained placenta. Her pregnancy was classified as high-risk with a Poedji Rochjati score is 22. The patient was referred for HBV DNA testing after diagnosis, with education provided on the disease and vertical transmission prevention. Follow-up care was scheduled at a Type A hospital equipped for high-risk pregnancies. The baby will receive Hepatitis B vaccination and HBIG immediately after birth. Conclusion: Pregnancies complicated by reactive Hepatitis B require comprehensive management, including patient and family education, routine medical monitoring, and careful birth planning. The Continuity of Care (CoC) approach ensures ongoing monitoring from pregnancy through postpartum. Collaboration between the patient, family, and healthcare providers is essential for minimizing complications, preventing vertical transmission, and ensuring the safety of both mother and baby.