Natural oral care: Formulation and evaluation of a polyherbal toothpaste

Kudnar, Jatin Rajendra and Mirajgave, Swapnil Sanjay and Kumavat, Nandini Vitthal and Mandhare, Gurudeo Shivaji (2025) Natural oral care: Formulation and evaluation of a polyherbal toothpaste. International Journal of Science and Research Archive, 14 (3). pp. 496-503. ISSN 2582-8185

Herbal formulations are increasingly preferred over synthetic alternatives due to their natural origin and minimal side effects. This study aims to develop a safe and effective polyherbal toothpaste using Shikakai (Acacia concinna) extract as a natural foaming agent, replacing synthetic surfactants like Sodium Isethionate. The formulation incorporates Neem (Azadirachta indica), Clove (Syzygium aromaticum), Turmeric (Curcuma longa, API: Curcumin), and Aloe Vera (Aloe barbadensis), which offer multiple medicinal benefits such as reducing dental plaque, gingivitis, cavities, gum diseases, and mouth ulcers. Calcium Carbonate acts as a mild abrasive, while Menthol and Honey enhance freshness and antimicrobial efficacy. The surfactant is naturally derived from Shikakai pods, ensuring good foaming ability and optimal cleaning efficiency. The laboratory formulation was evaluated for pH, spreadability, homogeneity, stability, foaming ability, extrudability, and moisture content. In vitro studies assessed its antibacterial activity against both Gram-positive and Gram-negative bacteria, demonstrating significant zones of inhibition. The resulting formulation exhibited a brownish aromatic appearance, effective foaming, and strong antimicrobial potential, making it a safe and efficient herbal alternative for oral hygiene.