Machine Learning for Personalized Brain Stimulation: AI-Optimized Neuromodulation Treatments

Talati, Dhruvitkumar V. (2025) Machine Learning for Personalized Brain Stimulation: AI-Optimized Neuromodulation Treatments. International Journal of Science and Research Archive, 14 (3). pp. 331-338. ISSN 2582-8185

Neurological disorders, such as Parkinson's disease, essential tremor, and epilepsy, are debilitating conditions that affect millions of individuals worldwide. Current treatments, including pharmacological interventions and invasive surgical procedures, often have limited efficacy and can be associated with significant side effects. In recent years, neuromodulation therapies, which involve the targeted application of electrical or magnetic stimulation to specific regions of the brain, have emerged as a promising alternative approach for managing these neurological conditions. In this research paper, we explore the potential of machine learning techniques to enhance the precision and personalization of neuromodulation treatments. We examine how machine learning algorithms can be leveraged to analyze neuroimaging data, identify individualized biomarkers, and inform the design of targeted brain stimulation protocols. Through a review of the current literature, we discuss the progress and challenges in applying machine learning to neuroimaging and neuromodulation, with a focus on translating these advancements into clinical practice. We highlight the importance of developing robust evaluation methods to ensure the clinical utility and generalizability of machine learning-based neuromodulation approaches. Finally, we propose future research directions that aim to integrate machine learning, neuroimaging, and personalized neuromodulation to improve the management of neurological disorders and enhance the quality of life for patients.